Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin Matrix (PRFM) are regenerative treatments that harness the growth factors in your own blood to stimulate tissue repair, collagen production, and cellular renewal. At Hawaii Facial Plastic Surgery, PRP and PRFM are used for under-eye rejuvenation, hair restoration, and skin renewal — administered by our aesthetic nurses under Dr. Tan's physician-directed protocol.
Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin Matrix (PRFM) are among the most biologically elegant treatments in aesthetic medicine. Both are derived from a small sample of your own blood — processed to concentrate the platelets and growth factors responsible for tissue repair and regeneration — then reinjected or applied where renewal is needed.
Because they use your own blood, the risk of allergic reaction or rejection is essentially eliminated. The growth factors in PRP and PRFM signal the body to produce new collagen, stimulate cellular repair, improve vascular supply, and accelerate tissue healing — mechanisms that have been studied and applied in medicine for decades.
At Hawaii Facial Plastic Surgery, PRP and PRFM treatments are physician-directed and administered by our aesthetic nurses under Dr. Tan's clinical framework. Every treatment plan is based on your specific concern — under-eye hollowing, hair thinning, or skin quality improvement — not a templated protocol.
PRP is produced by spinning a blood sample in a centrifuge to separate and concentrate the platelet-rich layer of the plasma. The resulting solution is rich in growth factors — including PDGF, TGF-β, VEGF, and EGF — that stimulate collagen production, cellular repair, and tissue regeneration. PRP is typically used for hair restoration and skin rejuvenation applications where a more fluid consistency is appropriate.
PRFM is a more advanced preparation — processed without anticoagulants to produce a fibrin matrix that acts as a scaffold, holding the platelets and growth factors in place at the injection site for a longer release period. This sustained release amplifies and extends the regenerative effect compared to standard PRP. PRFM is particularly well suited for under-eye rejuvenation, where controlled placement and sustained growth factor delivery are critical.
PRP and PRFM treatments are offered widely — including at many non-physician-directed facilities. The difference at Hawaii Facial Plastic Surgery is that your treatment is part of a physician-designed plan. Dr. Tan determines whether PRP, PRFM, or a combination is appropriate for your specific concern. Placement in the under-eye area — one of the most delicate and vascularly complex areas of the face — requires the anatomical knowledge that comes from physician oversight. The treatment itself is administered by our aesthetic nurses, but the clinical plan is Dr. Tan's.
The under-eye area — the tear trough — is one of the most visible signs of facial aging and fatigue. Dark circles, hollowing, and a sunken appearance can make patients look years older and perpetually tired — regardless of how much they sleep.
PRFM injected into the tear trough delivers sustained growth factor stimulation — improving skin quality, increasing collagen density, and reducing the hollowing and discoloration that causes dark circles. Unlike hyaluronic acid filler in the tear trough — which carries risk of swelling, bluish discoloration (Tyndall effect), and irregularity — PRFM uses your own tissue-building factors for a more natural, gradual result.
PRP scalp injections are a well-studied treatment for androgenetic alopecia (pattern hair loss) and other forms of hair thinning. Growth factors in PRP stimulate dormant hair follicles, extend the growth phase of the hair cycle, and improve follicle health — producing measurable improvement in hair density and thickness over a series of treatments.
PRP hair restoration is appropriate for both women and men experiencing early to moderate hair thinning. It is not a replacement for hair transplant surgery in patients with significant hair loss — but for appropriate candidates, it is a meaningful non-surgical intervention that can slow progression and improve density.
PRP and PRFM can be applied to the skin surface following microneedling — or injected directly into areas of skin thinning, fine lines, and crepiness — to stimulate collagen production and improve overall skin quality. This is distinct from the use of PRP with SkinPen microneedling (where it is applied topically to enhance microneedling outcomes) and represents a standalone injectable regenerative approach.
Areas particularly responsive to PRP and PRFM skin injections include the perioral area (lines around the mouth), the neck, and areas of pronounced skin thinning.
Every PRP and PRFM treatment begins with a consultation — either as part of a Facial Longevity Assessment or as a standalone visit — to assess your specific concern and confirm the appropriate treatment approach.
On the day of treatment, a small blood sample is drawn — typically from the arm — and placed in a centrifuge. The processing takes approximately 10–15 minutes and produces a concentrated PRP or PRFM preparation. The prepared solution is then administered to the treatment area by our aesthetic nurses.
For hair restoration, PRP is injected across the scalp in the areas of thinning. For under-eye PRFM, the prepared fibrin matrix is placed precisely into the tear trough. For skin rejuvenation, PRP or PRFM is either applied topically following microneedling or injected into specific areas.
Mild redness and tenderness at the treatment site are normal and resolve within 24–48 hours. Results develop gradually over 4–8 weeks as the growth factors stimulate the body's natural regenerative response. A series of treatments is typically recommended for hair restoration and skin applications.
Request a ConsultationSessions: 1–3 · Results visible at 4–8 weeks · Minimal downtime
Sessions: 3–4 spaced 4–6 weeks apart · Maintenance every 6–12 months · Results visible at 3–6 months
Sessions: 2–3 · Can be combined with SkinPen microneedling · Results build over 4–8 weeks
Mild redness and tenderness · Resolves within 24–48 hours · Return to normal activities same day
Common questions about PRP and PRFM treatments at Hawaii Facial Plastic Surgery.
Schedule a consultation — our clinical team will assess your specific concern and recommend the right regenerative approach for your goals.